Treatment for Mercury toxicity:
- Treatment consists of introducing in the stomach, a source of sulfhydryl rich protein such as milk or raw eggs.
- As soon as mercury intoxication is suspected intramuscular injection of dimercaprol or penicillamine is given to chelate the mercury and accelerate its excretion.
- In the absence of the metal chelating agents, isotonic NaCl solution is infused in amounts as much as 10 its per day to produce a copious dieresis so as to protect the kidney from a high concentration of Hg.
Treatment for Lead toxicity:
- Lead poisoning can be cured by treatment with the chelating agent which strongly bind Pb2+. Thus Ca-chelate in solution is fed to the victim of Pb poisoning. Pb2+ displaces Ca2+ from the chelate and the resulting Pb – chelate is repeatedly excreted in the urine.
- Higher levels of lead poisoning are reduced with chelation therapy. A combination of intra muscular dimercaprol and calcium disodium edentate is used, sometimes followed by a course of oral penicillamine for long-term prophylactic chelation. In treating of acute poisoning by alkyl lead compounds, sedative, anti-convulsion, fluid and electrolyte therapy may be required.
Treatment for Arsenic toxicity:
- Acute Arsenic poisoning has treated the antidote, dimercaprol. Restoration
of fluid and electrolyte balance is mandatory. - The alternative sources such as sand filters, infiltration galleries, or ranney wells, and in some place even rainwater harvesting can be adopted to alleviate the arsenic disaster.
- Coagulants such as the salt of aluminum and iron should be used to remove the arsenic from domestic drinking water.
Treatment for Cadmium toxicity:
- Standard chelation therapy using calcium disodium ethylenediamine tetraacetic acid (EDTA).
- Standard chelation therapy using British anti-Lewisite (BAL or dimercaprol).
** This article was posted by
Md. Jahangir Alam
M.Sc. Student
Department of Chemistry
RU