Level: Ph.D    
Host: Cancer Research UK Cambridge Institute

          Cambridge University

Supervisor: Professor Sir Shankar Balasubramanian

The lab exploits both chemistry and biology to address fundamental mechanisms of genome function  While many genetic determinants of cancer are known, alternative nucleic acid secondary structures and chemically modified DNA (or RNA) bases can be epigenetic features of nucleic acids that are important to normal biology and in oncogenesis. The project will explore chemical modifications as epigenetic features and how these influence secondary structure formation and function in the genome of normal and cancer cells.

Preferred skills/knowledge

  • The student will be highly motivated, capable of independent thought and have excellent communication skills with the ability to work collaboratively.
  • Ideally, the candidate will have a strong background in molecular biology and/or biochemistry. A good knowledge of genomics and the chemistry/chemical biology of nucleic acids is highly desirable.


  • This studentship is funded by Cancer Research UK and includes full funding for University and College fees 
  • A stipend of £19,000 per annum, initially for 3 years, with funding for a further year possible as required.

No nationality restrictions apply to this Cancer Research UK funded studentship. Applications are invited from recent graduates or final year undergraduates who hold or expect to gain a first/upper second class degree (or equivalent) in a relevant subject from any recognised university worldwide.
Application Procedure 
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